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rna-seq expression data  (Santa Cruz Biotechnology)


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    Santa Cruz Biotechnology rna-seq expression data
    Rna Seq Expression Data, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 90 stars, based on 1 article reviews
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    (A) Heatmap of differentially expressed genes <t>from</t> <t>RNA-sequencing</t> analysis of A549 cells with stable RHOV knockdown (sh1, sh2) compared to control. Consistent transcriptional alterations across both shRNAs are observed, with enrichment of MYC-related gene signatures among downregulated transcripts. (B) Gene ontology (GO) of differentially expressed genes shows significant downregulation of pathways associated with RNA biosynthesis, mRNA catabolism, ribosomal assembly, and mitotic cell cycle—all known MYC-driven processes. Upregulated pathways include DNA damage response, chromatin organization, and endocytic trafficking. Enrichment scores are represented along with q-values. (C) Gene Set Enrichment Analysis (GSEA) using Hallmark gene sets confirms strong negative enrichment of hallmark MYC target gene sets (V1 and V2) and oxidative phosphorylation genes in RHOV knockdown cells, indicating suppression of both proliferative and metabolic MYC programs. (D) Expression of MYC was compared between high and Low RHOV expressing patients in four NSCLC patients’ datasets. The expression of MYC was significantly higher in high RHOV patients (Mann-Whitney test). (E, F and G) The patients’ samples with high expression of RHOV (which show poor survival, ) from three cohort, (E) EAC, (F) Microarray and (G) TCGA were divided into two groups based on MYC expression. The analysis shows that RHOV high patients with low MYC expression survive significantly better than the RHOV high patients with high MYC expression. The p-values and Hazard ration are shown.
    Rna Sequencing Rna Seq Expression Data, supplied by Broad Clinical Labs, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    rna seq expression data  (Human Protein Atlas)
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    a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), <t>while</t> <t>RNA-seq</t> data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).
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    a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), <t>while</t> <t>RNA-seq</t> data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).
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    rna-seq expression data  (Santa Cruz Biotechnology)
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    Santa Cruz Biotechnology rna-seq expression data
    a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), <t>while</t> <t>RNA-seq</t> data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).
    Rna Seq Expression Data, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rna-seq+expression+data/10__1016_slash_j__btre__2025__e00902-58-3-42?v=Santa+Cruz+Biotechnology
    Average 90 stars, based on 1 article reviews
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    gene expression and rna-seq data  (Biotechnology Information)
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    a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), <t>while</t> <t>RNA-seq</t> data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).
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    cross-species brain rna-seq expression data  (Human Protein Atlas)
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    Human Protein Atlas cross-species brain rna-seq expression data
    a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), <t>while</t> <t>RNA-seq</t> data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).
    Cross Species Brain Rna Seq Expression Data, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rna-seq+expression+data/pm40016860-134-2-9?v=Human+Protein+Atlas
    Average 90 stars, based on 1 article reviews
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    rna-seq expression data  (Human Protein Atlas)
    90
    Human Protein Atlas rna-seq expression data
    a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), <t>while</t> <t>RNA-seq</t> data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).
    Rna Seq Expression Data, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rna-seq+expression+data/pmc11866840__13229_2025_650_MOESM2_ESM-1-0-5?v=Human+Protein+Atlas
    Average 90 stars, based on 1 article reviews
    rna-seq expression data - by Bioz Stars, 2026-07
    90/100 stars
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    (A) Heatmap of differentially expressed genes from RNA-sequencing analysis of A549 cells with stable RHOV knockdown (sh1, sh2) compared to control. Consistent transcriptional alterations across both shRNAs are observed, with enrichment of MYC-related gene signatures among downregulated transcripts. (B) Gene ontology (GO) of differentially expressed genes shows significant downregulation of pathways associated with RNA biosynthesis, mRNA catabolism, ribosomal assembly, and mitotic cell cycle—all known MYC-driven processes. Upregulated pathways include DNA damage response, chromatin organization, and endocytic trafficking. Enrichment scores are represented along with q-values. (C) Gene Set Enrichment Analysis (GSEA) using Hallmark gene sets confirms strong negative enrichment of hallmark MYC target gene sets (V1 and V2) and oxidative phosphorylation genes in RHOV knockdown cells, indicating suppression of both proliferative and metabolic MYC programs. (D) Expression of MYC was compared between high and Low RHOV expressing patients in four NSCLC patients’ datasets. The expression of MYC was significantly higher in high RHOV patients (Mann-Whitney test). (E, F and G) The patients’ samples with high expression of RHOV (which show poor survival, ) from three cohort, (E) EAC, (F) Microarray and (G) TCGA were divided into two groups based on MYC expression. The analysis shows that RHOV high patients with low MYC expression survive significantly better than the RHOV high patients with high MYC expression. The p-values and Hazard ration are shown.

    Journal: bioRxiv

    Article Title: TGF/J Regulated Small GTPase RHOV interact with PEAK1 and drive MYC Expression to Promote Cellular Proliferation, Migration and Etoposide resistance

    doi: 10.1101/2025.04.18.649622

    Figure Lengend Snippet: (A) Heatmap of differentially expressed genes from RNA-sequencing analysis of A549 cells with stable RHOV knockdown (sh1, sh2) compared to control. Consistent transcriptional alterations across both shRNAs are observed, with enrichment of MYC-related gene signatures among downregulated transcripts. (B) Gene ontology (GO) of differentially expressed genes shows significant downregulation of pathways associated with RNA biosynthesis, mRNA catabolism, ribosomal assembly, and mitotic cell cycle—all known MYC-driven processes. Upregulated pathways include DNA damage response, chromatin organization, and endocytic trafficking. Enrichment scores are represented along with q-values. (C) Gene Set Enrichment Analysis (GSEA) using Hallmark gene sets confirms strong negative enrichment of hallmark MYC target gene sets (V1 and V2) and oxidative phosphorylation genes in RHOV knockdown cells, indicating suppression of both proliferative and metabolic MYC programs. (D) Expression of MYC was compared between high and Low RHOV expressing patients in four NSCLC patients’ datasets. The expression of MYC was significantly higher in high RHOV patients (Mann-Whitney test). (E, F and G) The patients’ samples with high expression of RHOV (which show poor survival, ) from three cohort, (E) EAC, (F) Microarray and (G) TCGA were divided into two groups based on MYC expression. The analysis shows that RHOV high patients with low MYC expression survive significantly better than the RHOV high patients with high MYC expression. The p-values and Hazard ration are shown.

    Article Snippet: RNA-sequencing (RNA-seq) expression data from The Cancer Genome Atlas (TCGA) project were downloaded from the Broad Institute GDAC Firehose platform ( https://gdac.broadinstitute.org ).

    Techniques: RNA Sequencing, Knockdown, Control, Phospho-proteomics, Expressing, MANN-WHITNEY, Microarray

    a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), while RNA-seq data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).

    Journal: Communications Medicine

    Article Title: Autoantibody repertoire analysis in paraneoplastic pemphigus reveals novel targets linked to mucocutaneous blistering and bronchiolitis obliterans

    doi: 10.1038/s43856-025-01335-2

    Figure Lengend Snippet: a Expression of paraneoplastic pemphigus (PNP) autoantigens in diffuse large B-cell lymphoma (DLBCL), follicular lymphoma, Burkitt’s lymphoma, and HIV-positive cervical cancer. The heatmap displays the proportion of samples with expression levels exceeding 10 RPKM. In addition to PNP autoantigens, the heatmap includes reference genes such as GAPDH (housekeeping gene), KRTAP4-7 (skin-specific), CD3 epsilon (T-cell-specific), and CD19 (B-cell-specific) for comparison. Tumor RNA-sequencing summary statistics were obtained from the NIH Center for Cancer Genomics and the Cancer Genome Characterization Initiative (CGCI), while RNA-seq data for normal tissues (ectocervix, endocervix, and EBV-transformed lymphocytes) were retrieved from the GTEx portal (v6p.v1.1.8). b Autoantibody signal intensities in patients with paraneoplastic pemphigus, stratified by the type of neoplasm. Autoantibodies were measured using a bead-based protein array in patients with paraneoplastic pemphigus (PNP, n = 84) and healthy controls (HC, n = 105). c The heatmap displays the proportion of samples with an autoantibody fluorescence signal >1000, categorized by the type of neoplasm group in patients with paraneoplastic pemphigus ( n = 46). Only neoplasms present in two or more patients are included. The color scale is consistent across heatmaps ( a ) and ( c ).

    Article Snippet: RNA-seq expression data for healthy subjects were retrieved from the Human Protein Atlas version 23.0 ( https://www.proteinatlas.org/ ), accessed 2023-12-13 (rna_single_cell_type.tsv, and rna_single_cell_cluster_description.tsv), and the GTEx portal (v6p.v1.1.8), accessed 2022-12-05.

    Techniques: Expressing, Immunopeptidomics, Comparison, RNA Sequencing, Transformation Assay, Protein Array, Fluorescence